Red cell production.

Red cell production.

Red blood cells (erythrocytes) are normally produced only in the bone marrow of adults, but during embryonic and fetal life erythropoiesis occurs in the liver, and during the second to the fifth month of fetal life it occurs in the spleen.' From the fifth month after gestation marrow production increases gradually, having begun to take over from the liver during late fetal and early neonatal li...

Humoral regulation of red cell production.

Interleukin-8 production in red blood cell incompatibility.

Hemolytic transfusion reactions (HTR) are characterized by fever, shock, organ system failure, intravascular coagulation, and possibly death. The same findings may be associated with sepsis. Neutrophils have been implicated in the pathogenesis of HTR, although a mechanism for neutrophil activation has not been shown. In addition, the possible role that cytokines may play in HTR has not been inv...

Red cell production in the mouse following treatment with vinblastine.

Stimulation of Red-cell Production in Myelofibrosis with Prednisolone.

PATIENTS with myelofibrosis are usually treated with repeated blood transfusions and occasionally with busulphan or by splenectomy (Britton, I963). Splenic irradiation is sometimes of value (Szur and Smith, 196I). Adrenocorticosteroids are mentioned only in connection with the control of thrombocytopenia by Britton (I963), while Wintrobe (196I) states that they are useless. Others, however, hav...